Peculiar Places: The Salient Green
The Salient Green is a rather unassuming inn and tavern located along the western edge of Shatron City. Not really much to look at, The Salient Green actually has a great reputation for its house brews. It has a variety of ales from Greenskin, a bitter drink with a kick like a mule, to Poinyear, which has a mild and smooth flavor. There’s also Halfbread, Shortsnout and Pinkie, among others.
The proprietor and brewmaster, Bartleby Groondson, does all his brewing in the basement and allows no one down there. His recipes are well-kept secrets, and the only information he’ll volunteer is that he uses a variety of flavors and spices from around the world.
There is a reason beyond mere “trade secrets” that Bartleby is so tight-lipped; the brews of The Salient Green harbor dark (and, some might say, disgusting) secrets. For example, the Greenskin is made from weeds and lichens taken from the goblin caves of the west… and some well-fermented goblin as well. Likewise, the Poinyear uses elf, the Halfbread halfling, etc. All of Bartleby’s brews have some sort of creature in them.
Encounters at The Salient Green
The PCs could be hired to track down a missing person, or to investigate a recent rash of kidnappings. Of course, their investigations would lead them eventually to The Salient Green.
Alternately, the PCs might stumble on the secret on accident. Perhaps an overly-rowdy barroom brawl sends one of them hurtling through the door down into the basement, which looks more like a butcher’s shop than a brewery. Human, elf and dwarf parts hang from hooks along the walls, and a head bobbles up and down in a bubbling pot.

A bit of motivation for the innkeeper wouldn’t hurt. I have hard time getting a handle on this one.
One possible story hook is that the innkeeper wants something dangerous. Hydra poison, say, of which even a single drop could be used to add flavour to an immense amount of consumables.
Maybe the players will do deed. What if the next task is a bit more grissly? How long will they go hunting whatever the innkeeper wants, even if compensated significantly?
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I see the innkeeper’s motivation as being the greatest motivator of them all: money. People love his brews, and that’s good enough. Of course, you could make him a cannibal or something, which would help explain how he discovered his talents, but I don’t think that’s really necessary.
What would be interesting in your hydra poison idea above is if he miscalculated and killed a bunch of people on accident… and then the PCs caught some heat for it. He could lay the blame on them, or the authorities might just find out that they helped him get the poison and go after them on their own.